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1996-03-09
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Document 0381
DOCN M9650381
TI [Microsporidiosis in patients with chronic diarrhea and AIDS, in HIV
asymptomatic patients and in patients with acute diarrhea]
DT 9605
AU Weitz JC; Botehlo R; Bryan R; Departamento de Medicina, Facultad de
Medicina (Campus Oriente),; Universidad de Chile, Santiago de Chile.
SO Rev Med Chil. 1995 Jul;123(7):849-56. Unique Identifier : AIDSLINE
MED/96093577
AB Microsporidia are intracellular protozoa that mainly affect AIDS
patients and chronic diarrhea, caused by the strains Enterocytozoon
bieneusi and Septata intestinalis, is the most common clinical
manifestation. The diagnosis is made in intestinal biopsies, however the
recently developed trichromic stain with chromotrope 2R, is able to
detect microsporidia in stools and has a good correlation with the
biopsy. Using this technique, we studied 43 asymptomatic HIV infected
subjects, 89 AIDS patients with chronic diarrhea and 186 patients with
acute diarrhea as controls. Thirty-three percent of patients with AIDS,
16.3% of HIV infected subjects and none of the individuals with acute
diarrhea had microsporidia in their stools (p < 0.05). In 15 patients
with AIDS we detected intermitted stool microsporidia shedding; this
finding should encourage repetitive examinations in negative cases. The
trichromic stain for microsporidia is proposed as a routine test in AIDS
patients with diarrhea.
DE Acquired Immunodeficiency Syndrome/*COMPLICATIONS/PARASITOLOGY Acute
Disease Adolescence Adult Aged Aged, 80 and over Child Child,
Preschool Diarrhea/*COMPLICATIONS/PARASITOLOGY English Abstract
Feces/PARASITOLOGY Female Human HIV Infections/COMPLICATIONS Infant
Male Microspora Infections/*COMPLICATIONS Middle Age JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).